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National Science Foundation Award #9111503

Mechanisms of Neuronal Excitation by Magnetically Induced Currents

 
Investigator(s): Dominique Durand (PI)
Sponsor: Case Western Reserve University, OH 44106 2163684510
Start Date/Expiration Date 1991-08-15 to 1995-01-31 (amended 1993-07-26)
Awarded Amount to Date: $253,000
Abstract: This project will study: i) the mechanisms of activation of neural tissue by magnetic stimulation; ii) calculate induced fields in various volume conductors; iii) simulate on the computer the effects of these fields using models of axons and neurons; and iv) design a coil capable of focussing the induced fields. This project also intends to test directly the efficacy of this coil in both the peripheral nervous system and the central nervous system (CNS). This combination of a theoretical with an experimental approach should generate useful and important information about the mechanisms of magnetic stimulation and the efficacy of focussing magnetic fields for the excitation of the nervous system. This non-invasive method of stimulation should provide clinicians with a powerful tool to study and map normal brain function as well as diagnose certain types of neural diseases provided that the mechanisms of the interactions between magnetic fields and neural tissue can be understood.
NSF Org: BES - Division of Bioengineering & Environmental Systems
Award Number: 9111503
Award Instrument: Continuing grant
Program Manager: K. M. Mudry
BES Division of Bioengineering & Environmental Systems
ENG Directorate for Engineering
NSF Program(s): BIOMEDICAL ENGINEERING, CROSS-DIRECTORATE PROGRAMS, HUMAN RESOURCES DEVELOPMENT, RESEARCH TO AID THE DISABLED, HUMAN RESOURCES DEVELOPMENT
Field Application(s): Engineering NEC, Health
Program Reference Code(s): RESEARCH TO AID THE DISABLED, 5342
Program Element Code(s): 5345
CROSS-DIRECTORATE PROGRAMS, 9120
HUMAN RESOURCES DEVELOPMENT, 1360
RESEARCH TO AID THE DISABLED, 5342
, 1360